The fear of higher U.S. bond yields undermined riskier assets like U.S stocks and other global equities.
Stock experts had earlier anticipated that Pfizer would earn $12.7 billion from its COVID-19 vaccines sales in 2021.
Global businesses can now raise funds on the biggest and most liquid stock exchange in the world, through direct listings
The Dow Jones Industrial Average surged by 1.13%, while the NASDAQ Composite index gained 1.25%, and also S&P 500 index ticked up by 1.29%.
DoorDash has begun trading at the New York Stock Exchange, amid an era that has seen delivery firms gain significantly from skyrocketing demands.
At the close of the New Stock Exchange the S&P 500 index climbed 0.29%, Dow Jones Industrial Average gained 0.37%.
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Nigerian based Popular stock broking application, Bamboo, informed its users on Wednesday that it will no longer allow USD wire transfer options for deposits.
At the close of trading at the New York Stock Exchange, the Dow Jones Industrial Average surged by 1.55% to hit a new all-time high.
Apple Inc, the most valuable listed company, plunged in value by 3.17% to close at $106.84.