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Coronavirus

Moderna COVID-19 vaccine passes safety test on animals

Testing shows the vaccine enables antibody responses to obstruct the virus from infecting the mice cells.

Published

3 weeks ago

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Moderna COVID-19 vaccine passes safety test on animals

According to preliminary data, reported by Reuters, recent series of test carried on mice with Moderna Inc’s COVID-19 showed hope that it may not increase the risk of more serious diseases and that one dose may provide protection against the COVID-19 virus.

Prior test using the vaccine for SARS – a close cousin to the COVID-19 virus shows vaccines against such kind of virus might have an unexpected effect of causing more serious disease when the human vaccinated is exposed to the pathogen at a later phase, especially in humans who do not have strong immunity.

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“This is the barest beginning of preliminary information,” said Dr. Gregory Poland, an immunologist and vaccine researcher at the Mayo Clinic who has seen the paper, which has yet to undergo peer-review.

The authors said they have submitted their report to the leading journal. Moderna’s vaccine is in mid-level testing in healthy humans (volunteers). Moderna said lately it plans to begin the final trials enrolling about 30,000 people next month.

READ MORE: COVID-19: Hotels.ng partners others to provide self-isolation centres for Nigerians

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Using Moderna’s COVID-19 vaccine on, mice receiving one or two shots of different doses including doses considered not potent enough to facilitate a protective immune response. Lan scientists then exposed the mice to the virus.

“Sub protective doses did not prime mice for enhanced immunopathology following (exposure),” Dr. Barney Graham of the Vaccine Research Center at NIAID and colleagues wrote in the manuscript, posted on the bioRxiv website.

Further testing shows the vaccine enables antibody responses to obstruct the virus from infecting the mice cells.

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The COVID-19 vaccine also showed signs of protection against infection by the COVID-19 virus by shielding vital organs such as the lungs and noses without side effects, the research team wrote.

READ ALSO: American Business Council throws weight behind the Data Protection Bill

They stated that the mice which collected just one dose before exposure to the COVID-19 virus seven weeks later were completely immune against lung viral replication.

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“At first glance, it looks promising in inducing neutralizing antibody protection in mice,” Dr. Peter Hotez, a researcher at Baylor College of Medicine said in an email. He had not reviewed the paper in detail.

“The results, such as they are presented, provide interesting data that are reassuring … This needs to be replicated and it needs to be peer-reviewed,” he said.

 

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Olumide Adesina a French-born Nigerian, an Investment Professional at Nairametrics Financial Advocates, owners of Nairametrics.com. He is a Certified Investment Trader, with more than a decade working expertise in Investment Trading. A member of the Chartered Financial Analyst Society. Financial Market; Yale University, Behavioral Finance; Duke University. You can follow Olumide on twitter @tokunboadesina or email [email protected]

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Coronavirus

Pfizer’s COVID-19 vaccine shows positive results

The results encouraged moving to a larger clinical trial to test if the vaccine is actually safe.

Published

3 hours ago

on

July 2, 2020

By

WHO, Partners to deliver 2 billion doses of COVID-19 vaccines, Coronavirus blamed for Monday’s negative performance by Nigerian stocks, Experiment centre requests volunteers to infect with coronavirus and pay them N1.6 million, Airlines cut down capacity to raise capital, as Coronavirus takes a continuous hit at their revenue

An experimental COVID-19 vaccine being created by America’s pharmaceutical giant, Pfizer, and the German firm, BioNTech, activated immune responses in receivers more than individuals naturally recovering from an infection, according to a small journal published online yesterday.

However, the research work has not yet been certified by other medical experts and it is still unknown what degree of immune response will protect an individual from falling sick. Still, medical experts praised Pfizer for publishing the data on 45 people and said the results encouraged moving to a larger clinical trial to test if the COVID-19 vaccine is actually safe and effective for humans.

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“It’s the first positive data I’ve seen coming out of Operation Warp Speed,” Peter Jay Hotez, dean for the National School of Tropical Medicine at Baylor College of Medicine said to Washington Post, referring to the U.S. government effort to speed up the development, testing, and production of multiple coronavirus vaccines. “I’m really happy Pfizer took the initiative to publish it, whereas the others haven’t. I think we need to see more of this.”

Quick fact about COVID-19: Although for some individuals, the COVID-19 virus causes only mild illness, it can make other individuals seriously ill. The disease can be very fatal, especially among older individuals, and those with compromised immunities (such as diabetes, high blood pressure, or heart problems) appear to be more susceptible.

The 45 individuals were randomly selected in receiving injections of one of three different dose levels of the experimental COVID-19 vaccine. 21 days later, after the initial dose, they got a second one.

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Ugur Sahin, co-founder, and chief executive of BioNTech, told the Financial Times that his firm was going for a higher level of neutralizing antibody responses in order to increase the probability that those individuals vaccinated are prevented from spreading COVID-19 or being infected again.

“If you don’t know the level required to control this virus if you don’t know the power of the enemy, you don’t want the response to be too weak,” Sahin said.

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Coronavirus

COVID-19 Update in Nigeria

On the 1st of July 2020, 790 new confirmed cases and 13 deaths were recorded in Nigeria bringing the total confirmed cases recorded in the country to 26,484.

Published

9 hours ago

on

July 2, 2020

By

The spread of novel Corona Virus Disease (COVID-19) in Nigeria touched a new milestone as the latest statistics provided by the Nigeria Centre for Disease Control reveal Nigeria now has 26,484 confirmed cases.

On the 1st of July 2020, 790 new confirmed cases and 13 deaths were recorded in Nigeria, having carried out a total daily test of 4,205 samples across the country.

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To date, 26,484 cases have been confirmed, 10,152 cases have been discharged and 603 deaths have been recorded in 35 states and the Federal Capital Territory. A total of 138,462 tests have been carried out as of July 1st, 2020 compared to 134,257 tests a day earlier.

COVID-19 Case Updates- 1st July 2020

  • Total Number of Cases – 26,484
  • Total Number Discharged – 10,152
  • Total Deaths – 603
  • Total Tests Carried out – 138,462

According to the NCDC, the 790 new cases were reported from 21 states- Delta (166), Lagos (120), Enugu (66), FCT (65), Edo (60), Ogun (43), Kano (41), Kaduna (39), Ondo (33), Rivers (32), Bayelsa (29), Katsina (21), Imo (20), Kwara (18), Oyo (11), Abia (10), Benue (6), Gombe (4), Yobe (2), Bauchi (2), Kebbi (2).

Meanwhile, the latest numbers bring Lagos state total confirmed cases to 10,630, followed by Abuja (1,935), Oyo (1,391), Kano (1,257), Edo (1,165), Delta (1,131) Rivers (1,088), Ogun (869),  Kaduna (805), Katsina (578), Gombe (507). Bauchi (505), Borno (493), Ebonyi (438), Plateau (382), Imo (352), Enugu (327), Ondo (325), Abia (320), Jigawa (318).

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Kwara state has recorded 235 cases, Bayelsa (234), Nasarawa (213), Sokoto (151), Osun (127), Niger (116), Akwa Ibom (86), Adamawa (84), Kebbi (81), Zamfara (76), Anambra (73), Benue (65), Yobe (61), Ekiti (43), Taraba (19), while Kogi state has recorded 4 cases.

 

READ ALSO: COVID-19: Western diplomats warn of disease explosion, poor handling by government

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Lock Down and Curfew

In a move to combat the spread of the pandemic disease, President Muhammadu Buhari directed the cessation of all movements in Lagos and the FCT for an initial period of 14 days, which took effect from 11 pm on Monday, 30th March 2020.

The movement restriction, which was extended by another two-weeks period, has been partially put on hold with some businesses commencing operations from May 4. On April 27th, 2020, Nigeria’s President, Muhammadu Buhari declared an overnight curfew from 8 pm to 6 am across the country, as part of new measures to contain the spread of the COVID-19. This comes along with the phased and gradual easing of lockdown measures in FCT, Lagos, and Ogun States, which took effect from Saturday, 2nd May 2020, at 9 am.

On Monday, 29th June 2020 the federal government extended the second phase of the eased lockdown by 4 weeks and approved interstate movement outside curfew hours with effect from July 1, 2020.

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READ ALSO: Bill Gates says Trump’s WHO funding suspension is dangerous

DateConfirmed caseNew casesTotal deathsNew deathsTotal recoveryActive casesCritical cases
July 1, 2020264847906031310152157297
June 30, 202025694561590179746153587
June 29, 20202513356657389402151587
June 28, 20202486749056579007149957
June 27, 20202407777955848625148947
June 26, 20202329868455458253144917
June 25, 20202261459454977822142437
June 24, 20202202064954297613138657
June 23, 20202137145253387338135007
June 22, 20202091967552577109132857
June 21, 202020242436518126879128477
June 20, 202019808661506196718125847
June 19, 202019147667487126581120797
June 18, 20201848074547566307116987
June 17, 202017735587469145967112997
June 16, 202017148490455315623110707
June 15, 20201665857342445349108857
June 14, 202016085403420135220104457
June 13, 20201568250140785101101747
June 12, 20201518162739912489198917
June 11, 2020145546813875449496737
June 10, 20201387340938217435191407
June 9, 2020134646633654420688937
June 8, 2020128013153617404084007
June 7, 20201248626035412395981737
June 6, 2020122333893429382680657
June 5, 20201184432833310369678157
June 4, 2020115163503238353576467
June 3, 2020111663483151332975227
June 2, 20201081924131415323972667
June 1, 20201057841629912312271579
May 31, 20201016230728714300768687
May 30, 2020985555327312285667267
May 29, 202093023872612269763447
May 28, 202089151822595259260647
May 27, 202087333892545250159787
May 26, 2020834427624916238557107
May 25, 202080682292337231155247
May 24, 202078393132265226353607
May 23, 202075262652210217451317
May 22, 2020726124522110200750337
May 21, 2020701633921111190748987
May 20, 202066772842008184046377
May 19, 202064012261921173444757
May 18, 202061752161919164443407
May 17, 202059593881826159441837
May 16, 202056211761765147239737
May 15, 202054452881713132039544
May 14, 202051621931683118038154
May 13, 202049711841646107037374
May 12, 20204787146158695936704
May 11, 202046412421521090235894
May 10, 202043992481421777834794
May 9, 202041512391271174532784
May 8, 202039123861181067931154
May 7, 20203526381108460128184
May 6, 20203145195104553425071
May 5, 2020295014899548123704
May 4, 2020280224594641722912
May 3, 2020255817088240020702
May 2, 20202388220861735119522
May 1, 20202170238691035117512
April 30, 2020193220459731715562
April 29, 2020172819652730713692
April 28, 2020153219545425512322
April 27, 20201337644102559942
April 26, 20201273914152399942
April 25, 20201182873632229252
April 24, 202010951143312088552
April 23, 20209811083231977532
April 22, 2020873912931976482
April 21, 20207821172631975602
April 20, 2020665382311884662
April 19, 2020627862221704362
April 18, 2020541482021663562
April 17, 2020493511841593172
April 16, 2020442351311522772
April 15, 2020407341211282672
April 14, 202037330111992632
April 13, 202034320100912422
April 12, 20203235100852282
April 11, 202031813103702382
April 10, 20203051770582402
April 9, 20202881471512302
April 8, 20202742260442262
April 7, 20202541661442042
April 6, 2020238650351982
April 5, 20202321851331942
April 4, 2020214540251850
April 3, 20202092542251800
April 2, 20201841020201620
April 1, 2020174352091630
March 31, 202013982091280
March 30, 2020131202181210
March 29, 2020111221031070
March 28, 20208919103850
March 27, 2020705103660
March 26, 20206514102620
March 25, 2020517102480
March 24, 2020444102410
March 23, 20204010112370
March 22, 2020308002280
March 21, 20202210001210
March 20, 2020124001110
March 19, 20208000170
March 18, 20208500170
March 17, 20203100030
March 16, 20202000020
March 15, 20202000020
March 14, 20202000020
March 13, 20202000020
March 12, 20202000020
March 11, 20202000020
March 10, 20202000020
March 9, 20202100020
March 8, 20201000010
March 7, 20201000010
March 6, 20201000010
March 5, 20201000010
March 4, 20201000010
March 3, 20201000010
March 2, 20201000010
March 1, 20201000010
February 29, 20201000010
February 28, 20201100010

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Coronavirus

Update: Ondo State Governor, Akeredolu tests positive to coronavirus

Akeredolu now joins the list of top public officials that have contracted the disease.

Published

2 days ago

on

June 30, 2020

By

Spanish firm to meet Akeredolu over Ondo deep seaport project , Toll gate to be constructed along Akure-Ado road, Akeredolu says

The Governor of Ondo State, Rotimi Akeredolu, has tested positive to the coronavirus disease. He now joins the list of top public officials that have contracted the disease.

This was personally confirmed by the Governor through a tweet post on his official Twitter handle on Tuesday, June 30, 2020.

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According to his post, ‘’Today I tested positive to coronavirus disease. All is well, I’m asymptomatic and have been self-isolating. Work continues. Your continued prayers over my well-being are most appreciated.’’

READ ALSO: Why Nigerians, NCDC DG are opposed to the new NCDC bill

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The governor said that he had malaria a few days ago and was treated. However, he said that after the National Executive Council of his party, the APC, one of his colleagues advised that he should have a coronavirus test. He said that the result came out today, June 30 and he tested positive.

READ ALSO: N50 billion bond meant for road constructions – Ondo Governor

However, the governor pointed out that he was asymptomatic and is yet to show any symptom of the disease. He said although he is not feeling sick or odd in any way, his doctors advised that he should take the normal treatment and self-isolate as he believes that supervised home management will be ideal for him for now.

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Akeredolu also assured that work will be going on as he will be attending to files at home.

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The Ondo State Governor will be the latest high profile Nigerian to have contracted the disease. The immediate past Governor of Oyo State, Senator Abiola Ajimobi, passed away last week after a serious illness due to complications from the coronavirus disease.

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