Coronavirus
Moderna COVID-19 vaccine passes safety test on animals
Testing shows the vaccine enables antibody responses to obstruct the virus from infecting the mice cells.
According to preliminary data, reported by Reuters, recent series of test carried on mice with Moderna Inc’s COVID-19 showed hope that it may not increase the risk of more serious diseases and that one dose may provide protection against the COVID-19 virus.
Prior test using the vaccine for SARS – a close cousin to the COVID-19 virus shows vaccines against such kind of virus might have an unexpected effect of causing more serious disease when the human vaccinated is exposed to the pathogen at a later phase, especially in humans who do not have strong immunity.
“This is the barest beginning of preliminary information,” said Dr. Gregory Poland, an immunologist and vaccine researcher at the Mayo Clinic who has seen the paper, which has yet to undergo peer-review.
The authors said they have submitted their report to the leading journal. Moderna’s vaccine is in mid-level testing in healthy humans (volunteers). Moderna said lately it plans to begin the final trials enrolling about 30,000 people next month.
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Using Moderna’s COVID-19 vaccine on, mice receiving one or two shots of different doses including doses considered not potent enough to facilitate a protective immune response. Lan scientists then exposed the mice to the virus.
“Sub protective doses did not prime mice for enhanced immunopathology following (exposure),” Dr. Barney Graham of the Vaccine Research Center at NIAID and colleagues wrote in the manuscript, posted on the bioRxiv website.
Further testing shows the vaccine enables antibody responses to obstruct the virus from infecting the mice cells.
The COVID-19 vaccine also showed signs of protection against infection by the COVID-19 virus by shielding vital organs such as the lungs and noses without side effects, the research team wrote.
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They stated that the mice which collected just one dose before exposure to the COVID-19 virus seven weeks later were completely immune against lung viral replication.
“At first glance, it looks promising in inducing neutralizing antibody protection in mice,” Dr. Peter Hotez, a researcher at Baylor College of Medicine said in an email. He had not reviewed the paper in detail.
“The results, such as they are presented, provide interesting data that are reassuring … This needs to be replicated and it needs to be peer-reviewed,” he said.
Business News
COVID-19 Update in Nigeria
On the 11th of April 2021, 57 new confirmed cases and death was recorded in Nigeria
The spread of novel Corona Virus Disease (COVID-19) in Nigeria continues to record significant increases as the latest statistics provided by the Nigeria Centre for Disease Control reveal Nigeria now has 163,793 confirmed cases.
On the 11th of April 2021, 57 new confirmed cases and death was recorded in Nigeria.
To date, 163,793 cases have been confirmed, 154,107 cases have been discharged and 2,060 deaths have been recorded in 36 states and the Federal Capital Territory.
A total of 1.8 million tests have been carried out as of April 11th, 2021 compared to 1.7 million tests a day earlier.
COVID-19 Case Updates- 11th April 2021,
- Total Number of Cases – 163,793
- Total Number Discharged – 154,107
- Total Deaths – 2,060
- Total Tests Carried out – 1,803,177
According to the NCDC, the 57 new cases are reported from 7 states- FCT (20), Lagos (19), Bayelsa (7), Kaduna (4), Rivers (3), Osun (3) and Jigawa (1).
Meanwhile, the latest numbers bring Lagos state total confirmed cases to 57,969, followed by Abuja (19,723), Plateau (9,030), Kaduna (8,989), Rivers (6,999), Oyo (6,838), Edo (4,893), Ogun (4,621), Kano (3,930), Ondo (3,226), Kwara (3,120), Delta (2,617), Osun (2,553), Nasarawa (2,378), Enugu (2,259), Katsina (2,097), Gombe (2,034), Ebonyi (2,017), Anambra (1,909), Akwa Ibom (1,810), and Abia (1,683).
Imo State has recorded 1,655 cases, Bauchi (1,540), Borno (1,337), Benue (1,188), Adamawa (1,051), Niger (930), Taraba (910), Bayelsa (878), Ekiti (868), Sokoto (775), Jigawa (527), Kebbi (450), Cross River (385), Yobe (365), Zamfara (234), while Kogi state has recorded 5 cases only.
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Lock Down and Curfew
In a move to combat the spread of the pandemic disease, President Muhammadu Buhari directed the cessation of all movements in Lagos and the FCT for an initial period of 14 days, which took effect from 11 pm on Monday, 30th March 2020.
The movement restriction, which was extended by another two weeks period, has been partially put on hold with some businesses commencing operations from May 4. On April 27th, 2020, Nigeria’s President, Muhammadu Buhari declared an overnight curfew from 8 pm to 6 am across the country, as part of new measures to contain the spread of the COVID-19. This comes along with the phased and gradual easing of lockdown measures in FCT, Lagos, and Ogun States, which took effect from Saturday, 2nd May 2020, at 9 am.
On Monday, 29th June 2020 the federal government extended the second phase of the eased lockdown by 4 weeks and approved interstate movement outside curfew hours with effect from July 1, 2020. Also, on Monday 27th July 2020, the federal government extended the second phase of eased lockdown by an additional one week.
On Thursday, 6th August 2020 the federal government through the secretary to the Government of the Federation (SGF) and Chairman of the Presidential Task Force (PTF) on COVID-19 announced the extension of the second phase of eased lockdown by another four (4) weeks.
Governor Babajide Sanwo-Olu of Lagos State announced the closed down of the Eti-Osa Isolation Centre, with effect from Friday, 31st July 2020. He also mentioned that the Agidingbi Isolation Centre would also be closed and the patients relocated to a large capacity centre.
Due to the increased number of covid-19 cases in Nigeria, the Nigerian government ordered the reopening of Isolation and treatment centres in the country on Thursday, 10th December 2020.
On 26th January 2021, the Federal Government announced the extension of the guidelines of phase 3 of the eased lockdown by one month following the rising cases of the coronavirus disease in the country and the expiration of phase 3 of the eased lockdown.
On 28th February 2021, the federal government confirmed that the first tranche of Covid-19 vaccines will arrive in Nigeria on Tuesday, March 2nd, 2021.
On Tuesday, 2nd March 2021, the National Primary health Care Development Agency announced the arrival of the expected COVX Astrazeneca/Oxford covid-19 vaccines.
On Saturday, 6th March 2021, President Muhammadu Buhari and his vice, Yemi Osinbajo received vaccination against the covid-19 as the State House in Abuja.
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Business
Lagos eases restrictions on social, event centres, sets new occupancy limit
The state government has pegged the occupancy limit for event centres in Lagos to 500 people while social events can now have 200 people at a time.
The Lagos state government has further eased restrictions on social and event centres in the state. This follows due consultations and deliberations between the Lagos State Governor, Babajide Sanow-Olu, and relevant stakeholders and MDAs.
The state government has pegged the occupancy limit for event centres in Lagos to 500 people while social events can now have 200 people at a time.
This disclosure is contained in a statement by the Lagos State Commissioner for Tourism, Arts and Culture, Uzamat Yusuff, and the Director-General of the Lagos State Safety Commission, Mr Lanre Mojola, on Friday, April 9, 2021.
The statement noted that safety marshals will be deployed to any social event with over 200 people and event centre exceeding the 500 limits.
READ: Lagos Govt seals Queens Park Event Centre, Oniru for contravening COVID-19 protocol
The statement partly reads, “All event centres must hold a valid license of The Lagos State Ministry of Tourism, Arts and Culture prior to operating as an event centre in the State.
“All event centres must be duly registered and verified on The Lagos State Safety Commission website www.lasgsafetyreg.com prior to holding any event.
An Event Safety Clearance must be obtained from the Lagos State Safety Commission through the website www.lasgsafetyreg.com for any proposed event or exhibition.
Safety Marshals shall be deployed by an accredited event safety consultant from Lagos State Safety Commission for every social event with attendance exceeding over 200 people.
READ: Lagos state government reacts to reopening of event centers, clarify guidelines
Occupancy limit at any event must not exceed 50% of the maximum design capacity of the hall, wherein Occupancy Limit stickers provided by the Lagos State Safety Commission must be boldly posted at the entrance of the event hall.
Maximum allowable capacity for event centres irrespective of the occupancy limit is 500 people. Deep cleaning must be carried out before and after every event. Physical distancing shall be maintained between seated guests and a maximum number of seated guests should be 6 (six) people on a table of 10 persons.
Event duration should not exceed a maximum period of 6-hours. All guests and service providers at the facility must wear a nose mask and make use of hand sanitisers All guests and service providers must endeavour to wash their hands before entering the venue or in the alternative use hand sanitisers. Temperature checks must be taken at all entry points into a facility.
Guests and service providers with temperature (above 37.5) are to be politely turned back and referred to paramedics or the emergency response team on the ground. Hand sanitizers must be positioned at the entry points and different spots within the hall.
All event centres must endeavour to display standard COVID-19 safety signs. The signs must be bold and installed at conspicuous locations. Event centre owners/ planners/vendors would be responsible for any breach of protocols by their staff.”
In case you missed it
- It can be recalled that in July 2020, the Lagos State Government had issued fresh guidelines on the reopening of event and social centres following their shutdown as part of measures to contain the spread of the coronavirus pandemic.
- The state government insisted that the owners of such facilities must register with the government pending further directives.
FLASH: Lagos State Government has further eased restrictions on Social/Event centres in the State. This was disclosed today by the Commissioner for Tourism, Arts and Culture, Mrs. Uzamat Akinbile Yusuff and the DG, Lagos State Safety Commission, Mr. Lanre Mojola.@jidesanwoolu pic.twitter.com/Ai5KVOBfKC
— Jubril A. Gawat (@Mr_JAGs) April 9, 2021
