According to preliminary data, reported by Reuters, recent series of test carried on mice with Moderna Inc’s COVID-19 showed hope that it may not increase the risk of more serious diseases and that one dose may provide protection against the COVID-19 virus.
Prior test using the vaccine for SARS – a close cousin to the COVID-19 virus shows vaccines against such kind of virus might have an unexpected effect of causing more serious disease when the human vaccinated is exposed to the pathogen at a later phase, especially in humans who do not have strong immunity.
“This is the barest beginning of preliminary information,” said Dr. Gregory Poland, an immunologist and vaccine researcher at the Mayo Clinic who has seen the paper, which has yet to undergo peer-review.
The authors said they have submitted their report to the leading journal. Moderna’s vaccine is in mid-level testing in healthy humans (volunteers). Moderna said lately it plans to begin the final trials enrolling about 30,000 people next month.
Using Moderna’s COVID-19 vaccine on, mice receiving one or two shots of different doses including doses considered not potent enough to facilitate a protective immune response. Lan scientists then exposed the mice to the virus.
“Sub protective doses did not prime mice for enhanced immunopathology following (exposure),” Dr. Barney Graham of the Vaccine Research Center at NIAID and colleagues wrote in the manuscript, posted on the bioRxiv website.
Further testing shows the vaccine enables antibody responses to obstruct the virus from infecting the mice cells.
The COVID-19 vaccine also showed signs of protection against infection by the COVID-19 virus by shielding vital organs such as the lungs and noses without side effects, the research team wrote.
They stated that the mice which collected just one dose before exposure to the COVID-19 virus seven weeks later were completely immune against lung viral replication.
“At first glance, it looks promising in inducing neutralizing antibody protection in mice,” Dr. Peter Hotez, a researcher at Baylor College of Medicine said in an email. He had not reviewed the paper in detail.
“The results, such as they are presented, provide interesting data that are reassuring … This needs to be replicated and it needs to be peer-reviewed,” he said.
Pfizer’s COVID-19 vaccine shows positive results
The results encouraged moving to a larger clinical trial to test if the vaccine is actually safe.
An experimental COVID-19 vaccine being created by America’s pharmaceutical giant, Pfizer, and the German firm, BioNTech, activated immune responses in receivers more than individuals naturally recovering from an infection, according to a small journal published online yesterday.
However, the research work has not yet been certified by other medical experts and it is still unknown what degree of immune response will protect an individual from falling sick. Still, medical experts praised Pfizer for publishing the data on 45 people and said the results encouraged moving to a larger clinical trial to test if the COVID-19 vaccine is actually safe and effective for humans.
“It’s the first positive data I’ve seen coming out of Operation Warp Speed,” Peter Jay Hotez, dean for the National School of Tropical Medicine at Baylor College of Medicine said to Washington Post, referring to the U.S. government effort to speed up the development, testing, and production of multiple coronavirus vaccines. “I’m really happy Pfizer took the initiative to publish it, whereas the others haven’t. I think we need to see more of this.”
Quick fact about COVID-19: Although for some individuals, the COVID-19 virus causes only mild illness, it can make other individuals seriously ill. The disease can be very fatal, especially among older individuals, and those with compromised immunities (such as diabetes, high blood pressure, or heart problems) appear to be more susceptible.
The 45 individuals were randomly selected in receiving injections of one of three different dose levels of the experimental COVID-19 vaccine. 21 days later, after the initial dose, they got a second one.
Ugur Sahin, co-founder, and chief executive of BioNTech, told the Financial Times that his firm was going for a higher level of neutralizing antibody responses in order to increase the probability that those individuals vaccinated are prevented from spreading COVID-19 or being infected again.
“If you don’t know the level required to control this virus if you don’t know the power of the enemy, you don’t want the response to be too weak,” Sahin said.
COVID-19 Update in Nigeria
On the 1st of July 2020, 790 new confirmed cases and 13 deaths were recorded in Nigeria bringing the total confirmed cases recorded in the country to 26,484.
The spread of novel Corona Virus Disease (COVID-19) in Nigeria touched a new milestone as the latest statistics provided by the Nigeria Centre for Disease Control reveal Nigeria now has 26,484 confirmed cases.
On the 1st of July 2020, 790 new confirmed cases and 13 deaths were recorded in Nigeria, having carried out a total daily test of 4,205 samples across the country.
To date, 26,484 cases have been confirmed, 10,152 cases have been discharged and 603 deaths have been recorded in 35 states and the Federal Capital Territory. A total of 138,462 tests have been carried out as of July 1st, 2020 compared to 134,257 tests a day earlier.
COVID-19 Case Updates- 1st July 2020
- Total Number of Cases – 26,484
- Total Number Discharged – 10,152
- Total Deaths – 603
- Total Tests Carried out – 138,462
According to the NCDC, the 790 new cases were reported from 21 states- Delta (166), Lagos (120), Enugu (66), FCT (65), Edo (60), Ogun (43), Kano (41), Kaduna (39), Ondo (33), Rivers (32), Bayelsa (29), Katsina (21), Imo (20), Kwara (18), Oyo (11), Abia (10), Benue (6), Gombe (4), Yobe (2), Bauchi (2), Kebbi (2).
Meanwhile, the latest numbers bring Lagos state total confirmed cases to 10,630, followed by Abuja (1,935), Oyo (1,391), Kano (1,257), Edo (1,165), Delta (1,131) Rivers (1,088), Ogun (869), Kaduna (805), Katsina (578), Gombe (507). Bauchi (505), Borno (493), Ebonyi (438), Plateau (382), Imo (352), Enugu (327), Ondo (325), Abia (320), Jigawa (318).
Kwara state has recorded 235 cases, Bayelsa (234), Nasarawa (213), Sokoto (151), Osun (127), Niger (116), Akwa Ibom (86), Adamawa (84), Kebbi (81), Zamfara (76), Anambra (73), Benue (65), Yobe (61), Ekiti (43), Taraba (19), while Kogi state has recorded 4 cases.
Lock Down and Curfew
In a move to combat the spread of the pandemic disease, President Muhammadu Buhari directed the cessation of all movements in Lagos and the FCT for an initial period of 14 days, which took effect from 11 pm on Monday, 30th March 2020.
The movement restriction, which was extended by another two-weeks period, has been partially put on hold with some businesses commencing operations from May 4. On April 27th, 2020, Nigeria’s President, Muhammadu Buhari declared an overnight curfew from 8 pm to 6 am across the country, as part of new measures to contain the spread of the COVID-19. This comes along with the phased and gradual easing of lockdown measures in FCT, Lagos, and Ogun States, which took effect from Saturday, 2nd May 2020, at 9 am.
On Monday, 29th June 2020 the federal government extended the second phase of the eased lockdown by 4 weeks and approved interstate movement outside curfew hours with effect from July 1, 2020.
|Date||Confirmed case||New cases||Total deaths||New deaths||Total recovery||Active cases||Critical cases|
|July 1, 2020||26484||790||603||13||10152||15729||7|
|June 30, 2020||25694||561||590||17||9746||15358||7|
|June 29, 2020||25133||566||573||8||9402||15158||7|
|June 28, 2020||24867||490||565||7||9007||14995||7|
|June 27, 2020||24077||779||558||4||8625||14894||7|
|June 26, 2020||23298||684||554||5||8253||14491||7|
|June 25, 2020||22614||594||549||7||7822||14243||7|
|June 24, 2020||22020||649||542||9||7613||13865||7|
|June 23, 2020||21371||452||533||8||7338||13500||7|
|June 22, 2020||20919||675||525||7||7109||13285||7|
|June 21, 2020||20242||436||518||12||6879||12847||7|
|June 20, 2020||19808||661||506||19||6718||12584||7|
|June 19, 2020||19147||667||487||12||6581||12079||7|
|June 18, 2020||18480||745||475||6||6307||11698||7|
|June 17, 2020||17735||587||469||14||5967||11299||7|
|June 16, 2020||17148||490||455||31||5623||11070||7|
|June 15, 2020||16658||573||424||4||5349||10885||7|
|June 14, 2020||16085||403||420||13||5220||10445||7|
|June 13, 2020||15682||501||407||8||5101||10174||7|
|June 12, 2020||15181||627||399||12||4891||9891||7|
|June 11, 2020||14554||681||387||5||4494||9673||7|
|June 10, 2020||13873||409||382||17||4351||9140||7|
|June 9, 2020||13464||663||365||4||4206||8893||7|
|June 8, 2020||12801||315||361||7||4040||8400||7|
|June 7, 2020||12486||260||354||12||3959||8173||7|
|June 6, 2020||12233||389||342||9||3826||8065||7|
|June 5, 2020||11844||328||333||10||3696||7815||7|
|June 4, 2020||11516||350||323||8||3535||7646||7|
|June 3, 2020||11166||348||315||1||3329||7522||7|
|June 2, 2020||10819||241||314||15||3239||7266||7|
|June 1, 2020||10578||416||299||12||3122||7157||9|
|May 31, 2020||10162||307||287||14||3007||6868||7|
|May 30, 2020||9855||553||273||12||2856||6726||7|
|May 29, 2020||9302||387||261||2||2697||6344||7|
|May 28, 2020||8915||182||259||5||2592||6064||7|
|May 27, 2020||8733||389||254||5||2501||5978||7|
|May 26, 2020||8344||276||249||16||2385||5710||7|
|May 25, 2020||8068||229||233||7||2311||5524||7|
|May 24, 2020||7839||313||226||5||2263||5360||7|
|May 23, 2020||7526||265||221||0||2174||5131||7|
|May 22, 2020||7261||245||221||10||2007||5033||7|
|May 21, 2020||7016||339||211||11||1907||4898||7|
|May 20, 2020||6677||284||200||8||1840||4637||7|
|May 19, 2020||6401||226||192||1||1734||4475||7|
|May 18, 2020||6175||216||191||9||1644||4340||7|
|May 17, 2020||5959||388||182||6||1594||4183||7|
|May 16, 2020||5621||176||176||5||1472||3973||7|
|May 15, 2020||5445||288||171||3||1320||3954||4|
|May 14, 2020||5162||193||168||3||1180||3815||4|
|May 13, 2020||4971||184||164||6||1070||3737||4|
|May 12, 2020||4787||146||158||6||959||3670||4|
|May 11, 2020||4641||242||152||10||902||3589||4|
|May 10, 2020||4399||248||142||17||778||3479||4|
|May 9, 2020||4151||239||127||11||745||3278||4|
|May 8, 2020||3912||386||118||10||679||3115||4|
|May 7, 2020||3526||381||108||4||601||2818||4|
|May 6, 2020||3145||195||104||5||534||2507||1|
|May 5, 2020||2950||148||99||5||481||2370||4|
|May 4, 2020||2802||245||94||6||417||2291||2|
|May 3, 2020||2558||170||88||2||400||2070||2|
|May 2, 2020||2388||220||86||17||351||1952||2|
|May 1, 2020||2170||238||69||10||351||1751||2|
|April 30, 2020||1932||204||59||7||317||1556||2|
|April 29, 2020||1728||196||52||7||307||1369||2|
|April 28, 2020||1532||195||45||4||255||1232||2|
|April 27, 2020||1337||64||41||0||255||994||2|
|April 26, 2020||1273||91||41||5||239||994||2|
|April 25, 2020||1182||87||36||3||222||925||2|
|April 24, 2020||1095||114||33||1||208||855||2|
|April 23, 2020||981||108||32||3||197||753||2|
|April 22, 2020||873||91||29||3||197||648||2|
|April 21, 2020||782||117||26||3||197||560||2|
|April 20, 2020||665||38||23||1||188||466||2|
|April 19, 2020||627||86||22||2||170||436||2|
|April 18, 2020||541||48||20||2||166||356||2|
|April 17, 2020||493||51||18||4||159||317||2|
|April 16, 2020||442||35||13||1||152||277||2|
|April 15, 2020||407||34||12||1||128||267||2|
|April 14, 2020||373||30||11||1||99||263||2|
|April 13, 2020||343||20||10||0||91||242||2|
|April 12, 2020||323||5||10||0||85||228||2|
|April 11, 2020||318||13||10||3||70||238||2|
|April 10, 2020||305||17||7||0||58||240||2|
|April 9, 2020||288||14||7||1||51||230||2|
|April 8, 2020||274||22||6||0||44||226||2|
|April 7, 2020||254||16||6||1||44||204||2|
|April 6, 2020||238||6||5||0||35||198||2|
|April 5, 2020||232||18||5||1||33||194||2|
|April 4, 2020||214||5||4||0||25||185||0|
|April 3, 2020||209||25||4||2||25||180||0|
|April 2, 2020||184||10||2||0||20||162||0|
|April 1, 2020||174||35||2||0||9||163||0|
|March 31, 2020||139||8||2||0||9||128||0|
|March 30, 2020||131||20||2||1||8||121||0|
|March 29, 2020||111||22||1||0||3||107||0|
|March 28, 2020||89||19||1||0||3||85||0|
|March 27, 2020||70||5||1||0||3||66||0|
|March 26, 2020||65||14||1||0||2||62||0|
|March 25, 2020||51||7||1||0||2||48||0|
|March 24, 2020||44||4||1||0||2||41||0|
|March 23, 2020||40||10||1||1||2||37||0|
|March 22, 2020||30||8||0||0||2||28||0|
|March 21, 2020||22||10||0||0||1||21||0|
|March 20, 2020||12||4||0||0||1||11||0|
|March 19, 2020||8||0||0||0||1||7||0|
|March 18, 2020||8||5||0||0||1||7||0|
|March 17, 2020||3||1||0||0||0||3||0|
|March 16, 2020||2||0||0||0||0||2||0|
|March 15, 2020||2||0||0||0||0||2||0|
|March 14, 2020||2||0||0||0||0||2||0|
|March 13, 2020||2||0||0||0||0||2||0|
|March 12, 2020||2||0||0||0||0||2||0|
|March 11, 2020||2||0||0||0||0||2||0|
|March 10, 2020||2||0||0||0||0||2||0|
|March 9, 2020||2||1||0||0||0||2||0|
|March 8, 2020||1||0||0||0||0||1||0|
|March 7, 2020||1||0||0||0||0||1||0|
|March 6, 2020||1||0||0||0||0||1||0|
|March 5, 2020||1||0||0||0||0||1||0|
|March 4, 2020||1||0||0||0||0||1||0|
|March 3, 2020||1||0||0||0||0||1||0|
|March 2, 2020||1||0||0||0||0||1||0|
|March 1, 2020||1||0||0||0||0||1||0|
|February 29, 2020||1||0||0||0||0||1||0|
|February 28, 2020||1||1||0||0||0||1||0|
Update: Ondo State Governor, Akeredolu tests positive to coronavirus
Akeredolu now joins the list of top public officials that have contracted the disease.
The Governor of Ondo State, Rotimi Akeredolu, has tested positive to the coronavirus disease. He now joins the list of top public officials that have contracted the disease.
This was personally confirmed by the Governor through a tweet post on his official Twitter handle on Tuesday, June 30, 2020.
According to his post, ‘’Today I tested positive to coronavirus disease. All is well, I’m asymptomatic and have been self-isolating. Work continues. Your continued prayers over my well-being are most appreciated.’’
Today I tested positive for #COVID19. All is well. I'm asymptomatic and have been self isolating. Work continues. Your continued prayers over my well being are most appreciated. pic.twitter.com/P5UH0SmBiw
— Arakunrin Akeredolu (@RotimiAkeredolu) June 30, 2020
The governor said that he had malaria a few days ago and was treated. However, he said that after the National Executive Council of his party, the APC, one of his colleagues advised that he should have a coronavirus test. He said that the result came out today, June 30 and he tested positive.
However, the governor pointed out that he was asymptomatic and is yet to show any symptom of the disease. He said although he is not feeling sick or odd in any way, his doctors advised that he should take the normal treatment and self-isolate as he believes that supervised home management will be ideal for him for now.
Akeredolu also assured that work will be going on as he will be attending to files at home.
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The Ondo State Governor will be the latest high profile Nigerian to have contracted the disease. The immediate past Governor of Oyo State, Senator Abiola Ajimobi, passed away last week after a serious illness due to complications from the coronavirus disease.